Қазақ ұлттық қыздар педагогикалық университеті / Казахский национальный женский педагогический университет

Постоянный URI для этого сообществаhttps://cris.qyzpu.kz/handle/123456789/1

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Автор: search.filters.author.Ivan Mikirin

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    3D polarimetry of laser induced speckle fields for phase detection thyroid gland polycrystalline structure and traumatic necrosis of human internal organs
    (2024-12-16)
    Olexander G. Ushenko
    ;
    Oleksandr Vyacheslavovich Bilookyi
    ;
    Yuriy Ushenko
    ;
    Olexander V. Dubolazov
    ;
    Irina V. Soltys
    A short theory of the processes of formation of the laser speckle fields polarization structure of biological tissues with optically anisotropic architectonics is presented. A method of polarization interference mapping of speckle fields with layerby-layer phase scanning of holographically reconstructed distributions of complex amplitudes of biological preparations of various morphological structures and physiological states has been proposed and experimentally tested - biopsies of the thyroid gland and blood films of rats with different severity of sepsis. Layer-by-layer maps of polarization ellipticity of native histological sections of thyroid biopsies from donors and sick patients were studied. As part of the statistical analysis of phase coordinate distributions of polarization ellipticity, objective markers for the differential diagnosis of thyroid pathology were found - nodular goiter, autoimmune thyroiditis and papillary cancer. Very good (~90%) and excellent (≥90%) accuracy of differential diagnosis was achieved. Statistical markers for temporal monitoring of septic changes in polarization azimuth maps of polycrystalline blood films of rats were found. An example of further research using laser-induced autofluorescence polarimetry methods is presented.
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    Optical Sensor System for 3D Jones Matrix Reconstruction of Optical Anisotropy Maps of Self-Assembled Polycrystalline Soft Matter Films
    (Multidisciplinary Digital Publishing Institute, 2024-02-29)
    Waldemar Wójcik
    ;
    Zhengbing Hu
    ;
    Yuriy Ushenko
    ;
    Andrzej Smolarz
    ;
    Ірина Василівна Солтис
    Our work uses a polarization matrix formalism to analyze and algorithmically represent optical anisotropy by open dehydration of blood plasma films. Analytical relations for Jones matrix reconstruction of optical birefringence maps of protein crystal networks of dehydrated biofluid films are found. A technique for 3D step-by-step measurement of the distributions of the elements of the Jones matrix or Jones matrix images (JMI) of the optically birefringent structure of blood plasma films (BPF) has been created. Correlation between JMI maps and corresponding birefringence images of dehydrated BPF and saliva films (SF) obtained from donors and prostate cancer patients was determined. Within the framework of statistical analysis of layer-by-layer optical birefringence maps, the parameters most sensitive to pathological changes in the structure of dehydrated films were found to be the central statistical moments of the 1st to 4th orders. We physically substantiated and experimentally determined the sensitivity of the method of 3D polarization scanning technique of BPF and SF preparations in the diagnosis of endometriosis of uterine tissue.
    Цитирования (OpenAlex) 26