Показано: 1 - 4 из 4
  • Некоторые метрики заблокированы вашими 
    Тип записи:Публикация,
    RESEARCH OF GANODERMA LUCIDUM EXTRACTS’ ANTIOXIDATIVE AND MEMBRANE STABILLIZING PROPERTIES IN VITRO CONDITION
    (Shakarim University, 2024-09-27)
    A. N. Aralbaeva
    ;
    ;
    Gulzhan Zhamanbayeva
    ;
    Maira K. Murzakhmetova
    The using of bioactive compounds received from natural raw as nutriceutics is aknowledged as well as strengthening, immunomodulatory, adaptogenic agents and in order to reduce the risk of emergence of various diseases. Ganoderma Lucidum or Reishi mushroom is known on east during centuries and has been used in different aims. Modern researches of Reishi mushroom show its high antioxidative potential. Our experiments have shown that extracts made from micelium and fruiting body of ganoderma reduce the intensity of lipoperoxidation in membranes and increase the resistance in vitro conditions. Micelium extract inhibited the level of products of lipoperoxidation up to 37,6% at concentration 10 mkg, 21,1% at 20 mkg, 14,9% at 50 mkg. At influence the same concentrations of ascorbic acid means of level of lipid peroxidation amount 74,3%, 60,4% and 36,4% - respectively, for vitamin E - Е-70,2%, 65,3%, 53,5% and 38%respectively. Antioxidative effect of fruit body’s extract significantly have shown at 10-50 mkg – level of LPO decreased on 80% from origin level, the increasing of concentration from 50 to 100 mkg leaded to practically total inhibition of formation LPO products. At concentrations lower than 10 mkg antioxidative effect of the testing agents didn’t differ significantly. The experiments revealed that the mycelium extracts' antioxidant properties exceed the well-known antioxidant agents such as vitamins E and C, while the extract of the fruit body has a substantially similar effect of ascorbic acid and alpha-tocopherol Results of study have shown that extracts of ganoderma possess pronounced property to stabilize the structure of cell membrane. Severity of membrane stabilizing effect of extracts depended on concentration. In concentration 0-200 mkg in samples incubated in the presence of mycelium and fruit body extracts the hemolysis decreased on 19,8% and 25% at 10 mkg, on 27% and 37% at 20 mkg, on 55% and 57,2% at 50 mkg, on 63% and 68% at 100 mkg, on 69% and 65% at 200 mkg respectively, whereas at the introducing in samples the ascorbic acid in analogical concentrations the hemolysis have descended on 10%, 14,5%, 25%, 40% and 44%, and at the cariing in α-tocopherol the hemolysis lowered on 5%, 22%, 32%, 40%, 45% and 50% respectively. The researches of total polyphenols and flavonoids in extracts showed, that in extracts abscent compounds, which are related to flavonoids, whereas have found the existence of another polyphenolic compounds.
    Цитирования (OpenAlex) 3Цитирования (OpenCitations) 3
  • Некоторые метрики заблокированы вашими 
    Тип записи:Публикация,
    RESEARCH OF PROPERTIES OF LACTIC ACID BACTERIA STRAINS IN THE PRODUCTION OF BOILED-SMOKED AND SEMI-SMOKED PRODUCTS FROM HORSE MEAT
    (Shakarim University, 2025-11-03) ;
    Yasin M. Uzakov
    ;
    Leila A. Kaimbayeva
    ;
    Shynar Kenenbay
    ;
    Elmira Kuandykovna Assembayeva
    This study aims to investigate the effect of rosemary on the quality indicators of semi-smoked horse sausage. The study showed that rosemary powder possesses antioxidant properties for the sausage product during storage in a refrigeration chamber (at a temperature not exceeding 6 °C). The obtained results indicate that the use of plant raw materials with antioxidant properties as a functional and natural ingredient in the sausage product did not affect its color and texture. These findings suggest the possible application of rosemary to improve the oxidative stability of semi-smoked horse sausage. In addition, the use of a plantbased ingredient increases the biological value of the product and corresponds to modern trends in the production of functional meat products.
  • Некоторые метрики заблокированы вашими 
    Тип записи:Публикация,
    AUTOMATED CLASSIFICATION OF HEMODYNAMICALLY SIGNIFICANT ARRHYTHMIAS BASED ON ECG FEATURES
    (Shakarim University, 2026-01-25)
    Ainur Bekbay
    ;
    Zh. S. Bigaliyeva
    ;
    Vinera Baiturganova
    ;
    ;
    Zh. N. Issabekov
    This paper presents an automated method for the classification of hemodynamically significant arrhythmias (HSA) based solely on electrocardiographic (ECG) features, without the use of additional imaging diagnostic techniques. The proposed approach relies on key ECG parameters, including QRS complex duration, RR intervals, and heart rate (HR). The study is based on data from the open-access MIT-BIH Arrhythmia Database, which contains multiple types of cardiac rhythm disturbances. A comparative analysis of arrhythmia classes was conducted, leading to the identification of diagnostically significant predictors associated with hemodynamic instability. Logical decision rules and a decision tree model were developed to enable automatic recognition of HSA and clinical risk stratification. The proposed algorithm demonstrates high interpretability and practical applicability for real-time monitoring systems. The results confirm that ECG-based features alone can be effectively used for preliminary detection of dangerous arrhythmias. The developed approach is especially valuable for telemedicine systems and healthcare facilities with limited access to expensive diagnostic equipment.
  • Некоторые метрики заблокированы вашими 
    Тип записи:Публикация,
    ADSORBENTS BASED ON MODIFIED NANOCELLULOSE: WATER PURIFICATION FROM ORGANIC AND INORGANIC POLLUTANTS
    (Shakarim University, 2026-07-29)
    Zhexenbek Toktarbay
    ;
    Makhabbat Kunarbekova
    ;
    ;
    Kenes Kudaibergenov
    ;
    Dana Ashiraliyeva
    Against the backdrop of rapid industrial growth, water pollution has become a pressing global environmental issue. This review provides a systematic analysis of the efficiency of functionalized nanocellulose- based adsorbents for the removal of organic (synthetic dyes, phenols, antibiotics, pesticides) and inorganic (Pb 2+ , Cd 2+ , Hg 2+ , Cr(VI), Cu 2+ , As) pollutants from water. Key findings: the highest sorption capacities are achieved by TEMPO-oxidized nanocellulose and amine-functionalized composites – up to 2500 mg/g for methylene blue and up to 2270 mg/g for lead ions. Nanocellulose-based molecularly imprinted polymers (MIPs) selectively adsorb phenols with efficiencies of up to 97% even in the presence of structurally similar competitors. Most adsorbents reviewed retain 80+90% of their capacity after 20 regeneration cycles. The paper examines three main types of nanocellulose (CNC, NFC, BNC), their preparation methods (acid hydrolysis, TEMPO-oxidation, mechanical and enzymatic treatment), and surface functionalization strategies (isocyanate-based, amine- and thiol-functionalization). The alignment of nanocellulose production from agricultural waste (rice husks, soybean hulls) with sustainable development principles is emphasized. Key unresolved challenges – scale-up, stability in real wastewater matrices, and cost-effectiveness – and future research directions are also identified.