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Russian Journal of General Chemistry

ISSN
1070-3632
1608-3350
Издатель
Pleiades Publishing
Ключевые слова

Chemical Reaction Mec...

Inorganic and Organom...

Organophosphorus comp...

Structural and Chemic...

Phosphorus compounds ...

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    Тип записи:Публикация,
    New Derivatives of Coumarin-3-carboxylic Acid Containing a Furopyridine Fragment: Synthesis and Some Properties
    (Pleiades Publishing, 2025-08-01)
    Alexey Vladimirovich Trifonov
    ;
    Nurbol Orynbasaruly Appazov
    ;
    R. Kh. Bagautdinova
    ;
    Lyudmila K. Kibardina
    ;
    Michail A. Pudovik
    Abstract As a result of this study, the first representative of coumarin-3-carboxylic acid containing a furopyridine fragment was obtained. It was demonstrated that this coumarin-3-carboxylic acid readily forms salts with various organic amines, diamines, as well as with alkali metal cations (Na, K) and ammonia. Testing of all obtained compounds against tumor cell lines M-HeLa and HuTu 80 revealed that a number of salt structures (specifically those based on 2-aminopyridine, 2,6-diaminopyridine, or sodium) exhibit cytotoxicity comparable to the reference drug, 5-fluorouracil.
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