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The using of bioactive compounds received from natural raw as nutriceutics is aknowledged as well as strengthening, immunomodulatory, adaptogenic agents and in order to reduce the risk of emergence of various diseases. Ganoderma Lucidum or Reishi mushroom is known on east during centuries and has been used in different aims. Modern researches of Reishi mushroom show its high antioxidative potential. Our experiments have shown that extracts made from micelium and fruiting body of ganoderma reduce the intensity of lipoperoxidation in membranes and increase the resistance in vitro conditions. Micelium extract inhibited the level of products of lipoperoxidation up to 37,6% at concentration 10 mkg, 21,1% at 20 mkg, 14,9% at 50 mkg. At influence the same concentrations of ascorbic acid means of level of lipid peroxidation amount 74,3%, 60,4% and 36,4% - respectively, for vitamin E - Е-70,2%, 65,3%, 53,5% and 38%respectively. Antioxidative effect of fruit body’s extract significantly have shown at 10-50 mkg – level of LPO decreased on 80% from origin level, the increasing of concentration from 50 to 100 mkg leaded to practically total inhibition of formation LPO products. At concentrations lower than 10 mkg antioxidative effect of the testing agents didn’t differ significantly. The experiments revealed that the mycelium extracts' antioxidant properties exceed the well-known antioxidant agents such as vitamins E and C, while the extract of the fruit body has a substantially similar effect of ascorbic acid and alpha-tocopherol Results of study have shown that extracts of ganoderma possess pronounced property to stabilize the structure of cell membrane. Severity of membrane stabilizing effect of extracts depended on concentration. In concentration 0-200 mkg in samples incubated in the presence of mycelium and fruit body extracts the hemolysis decreased on 19,8% and 25% at 10 mkg, on 27% and 37% at 20 mkg, on 55% and 57,2% at 50 mkg, on 63% and 68% at 100 mkg, on 69% and 65% at 200 mkg respectively, whereas at the introducing in samples the ascorbic acid in analogical concentrations the hemolysis have descended on 10%, 14,5%, 25%, 40% and 44%, and at the cariing in α-tocopherol the hemolysis lowered on 5%, 22%, 32%, 40%, 45% and 50% respectively. The researches of total polyphenols and flavonoids in extracts showed, that in extracts abscent compounds, which are related to flavonoids, whereas have found the existence of another polyphenolic compounds.

The article examines the current status of populations of Phedimus hybridus (L.) 't Hart (also known as Sedum hybridum L. and Aizopsis hybrida (L.) Grulich) and Hylotelephium ewersii (Ledeb.) H. Ohba (formerly Sedum ewersii Ledeb.) in the Kok-Zhailau Gorge, part of the flora of the Ile Alatau. The study explores the biology of these species, including their population dynamics and life forms, as well as their ecological responses to specific ecological-cenotic conditions. P. hybridus is valued in traditional medicine for its diverse therapeutic properties, such as anti-inflammatory effects, stimulation of the nervous system, antidepressant and wound-healing actions, and inhibition of leukocytosis. In contrast, H. ewersii is commonly cultivated as an ornamental plant. The article also includes a taxonomic, ecological, and geographical analysis of the flora associated with the populations of P. hybridus and H. ewersii in the Kok-Zhailau Gorge.

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